Publish Date

August 21, 2024

Think back to high school biology class. You’re studying basic cell structure and learning about the function of each of the cellular organelles. Do you remember the mitochondria – the powerhouse of the cell? That little organelle stood out because it was responsible for supporting the actions of all the other organelles. It’s the engine of the cell and it makes everything go.

All human cells contain mitochondria except for red blood cells. The number of mitochondria in each cell is dependent upon how much energy the cells need. The cells of the heart, muscles and brain are always working so they need a lot of energy and house thousands of mitochondria per cell. Energy is produced in the form of adenosine triphosphate (ATP) and fuels all the functions of the cells, tissues, and organs.

This energy originally comes from the food that we eat and is converted into the chemical energy of ATP to be used by our cells. Proteins, fats, and carbohydrates get broken down into their component parts and are absorbed from our digestive tract into the bloodstream and eventually into the cells where the mitochondria use these components to make ATP to support all bodily functions. The mitochondria are the little engines that could!

But what happens if those little engines are not functioning optimally? Energy starts to wane, and bodily functions become sluggish. Hormone production, cellular detoxification, and protein formation are not occurring at the rate the body demands. We can feel this as a lack of energy. Our cells experience reduced functional capacity, and this has broad effects throughout the entire body.

Consuming an excess of simple carbohydrates can be damaging to the mitochondria because these carbs increase oxidative damage. Trans fats and too many polyunsaturated fatty acids are problematic for mitochondrial function as they are pro-inflammatory and like too many simple carbs increase oxidative stress. A well-balanced whole diet, along with time-restricted eating, where we eat all our meals in an 8 to 10-hour window of time, allows the mitochondria to repair and regenerate.

Screening for toxins such as heavy metals, environmental chemicals, and mycotoxins through reliable testing can identify which toxins may have the greatest impact on mitochondrial function. Mosaic Diagnostics has various tests available:

  • Metals – Nutrient + Toxic Elements testing provides detection of heavy metals and mineral imbalances via blood, hair, stool and urine assessment.
  • Environmental chemical detection through MosaicDX’s TOXDetect Profile provides evaluation for various toxic chemicals.
  • Mold toxin testing through MosaicDX’s MycoTOX Profile evaluates common mycotoxins. Most mycotoxins have adverse influences on mitochondrial function. 

Based on information from these tests, the implementation of detoxification methods can help greatly to reduce toxic burden. 

If energy is an issue, specific nutrients to support the function of the mitochondria can be very helpful. This can include L-carnitine, CoQ10, B-vitamins such as thiamine (B1), riboflavin (B2), niacin (B3), and pantothenic acid (B5), as well as magnesium. There are many mitochondrial support supplements available. 

To emphasize again the mitochondria are especially susceptible to nutrient deficiencies, toxins, and oxidative damage. Eating a diet rich in colorful veggies, quality sources of protein and omega-3 fats is supportive of mitochondrial health. Typically, the combination of a real food diet, along with selective support nutrients, is ideal for long-term for mitochondrial health.

Finally, an additional Mosaic Diagnostics to always consider with regards to mitochondrial dysfunction, and assessment for various nutrient imbalances, pathogen toxins, and other factors is the Organic Acids Test (OAT). The OAT is an essential test for anyone dealing with a chronic health condition, and the other tests mentioned above are complementary to the OAT. 

About the Author

Tracy Tranchitella, ND + Kurt Woeller, DO, FMAPS

Tracy Tranchitella, ND

Tracy Tranchitella is a Doctor of Naturopathic Medicine integrating the scientific principles of Functional Medicine with the sensibility and holistic view of traditional naturopathy. She provides naturopathic consultations for general health issues including digestive disorders, blood sugar management, autoimmune disorders, cardiovascular disease and metabolic disorders, chronic fatigue, hormone and menstrual issues and general dietary and nutritional consultations. With each patient, Dr. Tranchitella emphasizes a balanced whole-food diet coupled with important lifestyle strategies for stress management, quality sleep, regular exercise, and making time for the things that bring joy to our lives.

Dr. Tranchitella graduated from Southwest College of Naturopathic Medicine and has been in practice for 24 years. In addition to patient consultations, Dr. Tranchitella is co-founder of Integrative Medicine Academy with her partner Dr. Kurt Woeller. IMA provides in-depth courses in various areas of focus within Functional Medicine. For over 10 years, Dr. Tranchitella served as a Clinical Advisor for BioHealth Laboratory helping practitioners with lab interpretation and program development. Currently, she is a regular contributor to ZRT Laboratory’s blog which has developed into an extensive resource for patients and health care providers.

Dr. Tranchitella is a practicing partner at Sunrise Functional Medicine in Bend, Oregon.

 

Kurt Woeller, FMAPS, DO

FOUNDER OF INTEGRATIVE MEDICINE ACADEMY
Kurt N. Woeller, DO, FMAPS, is a Doctor of Osteopathic Medicine, integrative and functional medicine physician, and biomedical Autism Treatment Specialist in clinical practice for over 25 years.

Dr. Woeller is the education director and main course developer for his Integrative Medicine Academy (https://integrativemedicineacademy.com), an online academy for health professionals. He is also the Organic Acids Test (OAT) seminar creator and presenter for Mosaic Diagnostics Laboratory (formally Great Plains Laboratory’s GPL Academy) Mosaic EDGE seminars and has been involved in monthly educational webinars for GPL/Mosaic Diagnostics, and other organizations for over a decade.

His private practice, Sunrise Functional Medicine (https://mysunrisecenter.com), focuses on specialized diagnostic testing and treatments for individuals with complex medical conditions like autism, autoimmune, gastrointestinal, certain neurological disorders, and other chronic health conditions. Dr. Woeller is a Fellow of the Medical Academy of Pediatric Special Needs (MAPS).

He has served as a clinical consultant for various laboratory companies, i.e., Great Plains Laboratory, BioHealth Laboratory, providing health practitioner education regarding functional and integrative medicine.

You can follow Dr. Woeller for ongoing education articles and videos through his Substack at https://drwoeller.substack.com/ and his YouTube channel for Integrative Medicine Academyhttps://www.youtube.com/@integrativemedicineacademy. Finally, listen to Dr. Woeller’s latest health professional interviews through his Functional Medicine Doc Talk Podcast – https://functionalmedicinedoctalk.com.