Publish Date

September 1, 2022

On August 5-7, 2022, Mosaic EDGE (formerly GPL Academy) hosted the Mitochondria and Toxins: Advanced Strategies & Protocols in Chicago and live-streamed online. The following Q+A is a grouping of responses from the workshop presentations.

The material contained within this article is not intended to replace the services and/or medical advice of a licensed healthcare practitioner, nor is it meant to encourage diagnosis and treatment of disease. It is for educational purposes only. Any application of suggestions set forth in the following portions of this article is at the reader’s discretion and sole risk. Implementation or experimentation with any supplements, herbs, dietary changes, medications, and/or lifestyle changes, etc., is done so at your sole risk and responsibility.

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Q: How much more is covered in your Advanced OAT Mastery Course?

A: We go over every marker on the Organic Acids Test from Great Plains, as well as certain other markers commonly seen on other OATs.

Q: Do you ever delay addressing the bacterial/fungal dysbiosis to gently detox the patient first so that the removal of the biofilm is more effective and is only done once?

A: Yes, this can be done for some people.

Q: I have a patient who gets recurrent vaginal yeast infections monthly. She is told by her gynecologist that it’s hormonal. Could it be from a yeast/mold issue within the gut and environment? Should I run an Organic Acids Test on her?

A: Absolutely run an OAT.

Q: Do you typically avoid fungus plants in mold/mycotoxin patients? Do you use saccharomyces boulardii?

A: I use this from time to time. It can be helpful overall, but some people are sensitive to it.

Q: If the test shows candida or mold does that mean it is currently active?

A: On the OAT its active.  

Q: Or could it be showing that you did at one time have candida and there are antibodies or organic acids still present?

A: The IgG Food MAP can indicate past problems, but the OAT is current and active.

Q: Once you see the clostridia markers high on the OAT, do you run a stool test to confirm Clostridia presence before treating?

A: No, only unless they have significant bowel problems and want to rule out C. difficile with toxins and A and B.

Q: Polyethylene glycol is used widely in nursing homes for older people with constipation. It is also a component in some drugs and foods, how much of a health risk is this?

A: It’s a risk and certainly not ideal to use. There are many other options for constipation in the natural medicine world worth looking into.

Q: I understand, from other information I’ve viewed, that the OAT can be hit-or-miss for oxalates because of cyclical excretion. Are you familiar with this phenomenon or its implications?

A: Yes. It’s called dumping. However, most of the time it is picked up on the OAT.

Q: For patients taking high doses of quercetin ascorbate (i.e. 2-8g/day) for mast cell hyperactivity, do you think there is a high probability of oxalate issues from such high doses of Vitamin C? Would a downward taper be a good idea, to avoid possible dumping when coming off it again?

A: Yes. Oxalates can manifest through this. For people who are very sensitive this would be a good idea. Not necessary for many people though.

Q: I’ve heard of good results with AURO topical glutathione. Your thoughts? Have you used it? vs Tri Fortify?

A: I have not used it.

Q: Would ADD medication affect the HVA value on the OAT?

A: Anything that drives up dopamine can affect the HVA value.

Q: What D-lactic free probiotics do you use/how do you know if the probiotic is D-lactic free?

A: It has to do with the type of bacteria in the probiotic. You will need to do some research on which bacteria produce D-lactic.

Q: Which marker on the OAT could indicate a coinfection of virus interfering with mitochondria function or getting damaged inducing the cell danger response?

A: There is no specific marker for viruses and no markers per se specific to the CDR.

Q: Do you have any thoughts or preferences on the form of CoQ10 to use, ie. Ubiquinol or Ubiquinone?

A: Ubiquinol.

Q: Do you have any thoughts on supplementing with Calcium Citrate for Oxalates and K2 amounts to address uptake? Does it matter if the Calcium is getting bound with the oxalates?

A: Vitamin K helps with bone mineralization so less availability for oxalate binding. It is a good idea to use too.

Q: Do molds that are known to be toxic that show up on the OAT not always produce toxins that would show up on the MycoTOX Profile?

A: Correct. There may not always be mycotoxins present, but they often are.

Q: Is Gliotoxin just produced by fungus or also candida?

A: There seems to be controversy around it, but it appears more likely that Candida can produce it too.

Q: Do you avoid using saccharomyces boulardii as an antifungal in those with fungal or mold related illness due to it being in that family of organisms, or do you find it still beneficial?

A: I do not use SB a lot. It can be helpful for some people, but watch out for reactions in people with inflammatory bowel disease.

Q: Can colonized molds create mycotoxins?

A: Yes

Q: Does the nephrotoxicity associated with ochratoxin, etc, tend to reverse once the detoxification has been done? 

A: It should if the problem has been more of a recent onset.

Q: Any experience using modified citrus pectin?

A: Some. It is another type of binder.

Q: At what level of a positive MycoTOX Profile do you treat mycotoxins? 

A: Any level outside the green. If its in the green than I mostly leave it alone unless the patient has known exposure and there is a high suspicion of mold/mycotoxin exposure.

Kurt N. Woeller, DO

About the Author


Kurt N. Woeller, D.O. has been an integrative medicine physician and biomedical Autism specialist for over 20+ years. He is an author of several health books including Autism – The Road To Recovery, Methyl-B12 Therapy For Autism, Methyl-B12 for Alzheimer’s Disease and Dementia, and 5 Things You MUST Do Right Now To Help With Your Rheumatoid Arthritis. He is an international speaker, educator, and practicing clinician offering specialized interventions for individuals with complex medical conditions. His health consulting practice for Autism alone is multinational with families from various countries. Dr. Woeller serves as a clinical and lab consult for Functional Medicine Clinical Rounds, as well as provides educational seminars for Great Plains Laboratory. He is co-founder of Integrative Medicine Academy (, which is an online training academy for health practitioners learning integrative medicine.