Discover the Root Cause
The next generation of Lyme + Co-Infection Diagnostics—designed to detect at every stage.
Testing for Lyme disease and co-infections in combination provides a more comprehensive assessment of tick and vector-borne exposures. MosaicDX Lyme + Co-infection combination panels streamline the identification process, reduce costs, and offer unparalleled visibility into health factors, ensuring prompt and effective treatment.
Who might benefit from assessing
Lyme + Co-infections?
Patients presenting with flu-like symptoms, with or without Erythema migrans (EM) rash, and have lived or traveled to an area where Lyme disease is endemic.
Patients with chronic illness not improving, and past/present exposure to ticks, even with past treatment of Lyme, or Post-Treatment Lyme Disease Syndrome (PTLDS) or co-infections.
Patients with chronic illness not improving, and past/present exposure to ticks, fleas, lice, spiders or companion animals.
- Abdominal pain
- Anorexia
- Anxiety and depression
- Arthritis
- Bladder and pelvic pain
- Body aches
- Cardiovascular issues (endocarditis)
- Carditis or heart block
- Changes in bowel habits
- Depression
- Eye and vision problems (such as floaters, light sensitivity, and blurry vision)
- Facial pain and tooth issues
- Fatigue / chronic fatigue / profound fatigue
- Fever
- Fibromyalgia
- Flu-like illness
- Headaches
- Joint pain
- Localized or disseminated EM
- Malaise
- Muscle pain / soreness
- Muscle/limb impairment or paralysis
- Neurological manifestations
- Neurological symptoms such as facial paralysis, blindness
- Psychiatric symptoms (rage)
- Rash “striae”
- Seizures
- Sleeplessness
- Swollen lymph nodes in the head, neck, arms, and along the shins
Our Tests
View All TestsMosaicDX offers the next generation of Lyme + Co-Infection testing—designed to detect at every stage. Our Lyme + Co-infection tests and combination panels are available in urine, serum, and blood.
 |
Lyme Borrelia Direct Detect | Bartonella IgG Detect – IFA | Tickborne BBB Direct Detect (1 or 3 day) |
|---|---|---|---|
| Methodology | Nanotrap® Direct |
Immuno-fluorescence (IFA) Indirect |
Digital PCR (dPCR) Direct |
| Sample Type |  Urine |
 Serum (yellow top) |
 Blood (lavender top) |
| INDIVIDUAL PROFILES | |||
| Lyme Borrelia Direct Detect | ✓ | ||
| Bartonella IgG Detect – IFA | ✓ | ||
| Tickborne BBB Direct Detect – 1 day Tickborne BBB Direct Detect – 3 day |
✓ | ||
| COMBINATION PROFILES | |||
| Lyme + Bartonella – 1 day | ✓ | ✓ | |
| Lyme + Co-infections Comprehensive – 1 day Lyme + Co-infections Comprehensive – 3 day |
✓ | ✓ | ✓ |
| Tickborne BBB Plus – 1 day Tickborne BBB Plus – 3 day |
✓ | ✓ | |
Lyme + Bartonella – 1 day:
This profile combines Lyme Borrelia Direct Detect – Nanotrap® with Bartonella IgG Detect – IFA for analysis of the two most common vector-borne disease causing pathogens in North America.
Lyme Borrelia Direct Detect Nanotrap confirms current infection by detecting OspA antigen in easy-to-collect urine samples.
Bartonella IgG Detect IFA confirms antibodies against the four most common species of infection in North America; Bartonella henselaeBartonella koehlerae, Bartonella quintana, and Bartonella vinsonii berkhoffii.
We offer 9 individual tests and combinations of the most common Lyme and co-infections in North America, with options designed to meet every practitioner’s need.
Lyme + Co-infections Comprehensive 1 day:
Our most comprehensive Lyme and co-infection combination panel includes Tickborne BBB Direct Detect dPCR with the Lyme Borrelia Nanotrap® urine antigen test to provide optimal coverage for the top flea and tick-borne infections at the genus level. Bartonella IgG Detect IFA adds enhances diagnostic accuracy when combined with BBB Direct Detect species genus level digital PCR Bartonella results.Tickborne BBB Direct Detect – dPCR (1 day or 3 day) and Lyme Borrelia Direct Detect – Nanotrap® and Bartonella IgG Detect – IFA
Tickborne BBB Direct Detect dPCR, confirms current infection by directly detecting genus-level DNA for a broad range of Bartonella, Borrelia, and Babesia species (spp) in whole blood.
Lyme + Co-infections Comprehensive 3 day:
Our most comprehensive Lyme and co-infection combination panel includes Tickborne BBB Direct Detect dPCR with the Lyme Borrelia Nanotrap® urine antigen test for optimal coverage for the top flea and tick-borne infections at the genus level. Bartonella IgG Detect IFA adds enhances diagnostic accuracy when combined with BBB Direct Detect species genus level digital PCR Bartonella results.Tickborne BBB Direct Detect – dPCR (1 day or 3 day) and Bartonella IgG Detect – IFA and Lyme Borrelia Direct Detect – Nanotrap
Tickborne BBB Direct Detect + Bartonella IgG Detect IFA
Tickborne BBB Direct Detect dPCR, confirms current presence of pathogens by directly detecting genus-level DNA for a broad range of Bartonella, Borrelia, and Babesia species (spp) in whole blood.
The Lab Testing Experience, Simplified
Focus on delivering personalized care to your patients, not on navigating complicated lab test ordering processes.
Intuitive Portal
Effortless ordering, pricing, updates and results through our user-friendly dashboard.
Digital Test Requisition
Get more done in less time with our convenient online kit registration.
Simplified Sample Collection
Easy steps, visual instructions, proactive guidance, better results.
Easy to Interpret Results
We translate complex data into easy-to-understand clinical insights.Explore our Lyme + Co-infections Resources
View All Resources
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