Dr. William Shaw, Ph.D. Bio William Shaw, Ph.D., is board certified in the fields of clinical chemistry and toxicology by the American Board of Clinical Chemistry. Before he founded The Great Plains Laboratory, Inc., Dr. Shaw worked for the Centers for Disease Control and Prevention (CDC), Children’s Mercy Hospital, University of Missouri at Kansas City […]
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Specific Toxic Substances and the OAT Mold Exposure Mold exposure, often an overlooked influence on chronic illness, can be challenging to detect. The OAT can further assist in this detection process by looking at fungal activity and mycotoxin metabolism versus exclusive excretion of mycotoxins. Specific organic acid markers such as 5-Hydroxymethyl-2-furoic acid (HMFA), Furan-2,5-dicarboxylic acid, […]
William Shaw, PhDIMCJ Integrative Medicine • Vol. 16, No. 1 • February 2017 Abstract Context: Autism is a neurodevelopmental disorder for which a number of genetic, environmental, and nutritional causes have been proposed. Glyphosate is used widely as a crop desiccant and as an herbicide in fields of genetically modified foods that are glyphosate resistant. Several […]
William Shaw, PhDAutism Parenting Magazine, Issue 66 After working on the causes of autism for almost 25 years, one of the most fascinating and puzzling aspects has been the marked increase in autism that has been noted over the last 30 years. To qualify as a cause of autism, the factor needs to be something […]
The dysbiosis marker 3-(3-hydroxyphenyl)-3-hydroxypropionic acid (HPHPA), the predominant dihydroxyphenylpropionic acid isomer in urine, is also measured in the Organic Acids Test offered by MosaicDX. This marker was proven by Dr. William Shaw to be due to a combination of human metabolism and the metabolism by a group of Clostridia species, including but not limited to C. […]
Introduction One of the puzzling aspects of autism is the marked increase in the incidence of autism that began in the United States in the early 1980s and has appeared to increase continuously since then. The highest incidence of autism has been reported to be South Korea, where the incidence is now reported to be […]
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Chronic candida has been a well-recognized problem in functional and integrative medicine for many years. It too is a problem acknowledged in conventional medicine, although at times for different reasons, i.e., oral thrush or skin infections. Candidiasis is defined as a fungal infection linked to any form of candida species. These infections can occur in […]
William Shaw, PhD; Matthew Pratt-Hyatt PhDTownsend Letter – November 2019 Abstract Seven different mycotoxins, including aflatoxin M1, ochratoxin A, sterigmatocystin, zearalenone, roridin E, verrucarin A, and enniatin B1 that have been associated with human illness were tested by LC/MS/ MS in urine samples of a control group of 89 healthy adult volunteers and 103 adult […]
TEST IMPLICATIONS FOR YEAST AND HEAVY METALSWILLIAM SHAW, PH.D. What are Oxalates? Oxalate and its acid form oxalic acid are organic acids that are primarily from three sources: the diet, from fungus such as Aspergillus, Penicillium, and possibly Candida (1-9), and also from human metabolism (10). Oxalic acid is the most acidic organic acid in […]
William Shaw, PhD, discusses the clinical utility of IgG food allergy testing, use in creating elimination diets, ELISA test methodology, and total IgG vs. IgG 4. Immunoglobulin G (IgG) food allergy testing has made vast advancements since the year 2003 when the American Academy of Allergy, Asthma, and Immunology published a statement that “Measurement of […]