Case Study: Rapid Complete Recovery from an Autism Spectrum Disorder after Treatment of Aspergillus with the Antifungal Drugs Itraconazole and Sporanox

Sidney Baker, MD; William Shaw, PhDIMCJ Integrative Medicine • Vol. 19, No. 4 • August 2020 Abstract Context: A child with symptoms placing him within the autism spectrum and with urine biochemical markers consistent with fungal (Aspergillus) colonization of the gastrointestinal tract was first treated with the antifungal probiotic Saccharomyces boulardii. A dramatic Herxheimer reaction provided strong clinical indications that […]

Psychiatry Redefined, the Evolution of Psychiatry: From the Measureless Medicine to Precision Healing

Townsend Letter – January 2019 Measuring the Mind Measurement is the basis of all scientific medicine. Clinical diagnoses, treatments, and success rates all rely on definitive, quantifiable data that can be accurately assessed, evaluated, and monitored. Numbers allow physicians to create comparable references and scales that identify and characterize a condition and its severity. Discrete data […]

Clostridia Bacteria, Autism, and the Organic Acids Test (OAT)

The material contained within this presentation is not intended to replace the services and/or medical advice of a licensed healthcare practitioner, nor is it meant to encourage diagnosis and treatment of disease. It is for educational purposes only. Any application of suggestions set forth in the following portions of this article is at the reader’s […]

The Organic Acid Test (OAT) & Autism: A Scientific Breakthrough in Care

Dr. William Shaw, Ph.D. Bio William Shaw, Ph.D., is board certified in the fields of clinical chemistry and toxicology by the American Board of Clinical Chemistry. Before he founded The Great Plains Laboratory, Inc., Dr. Shaw worked for the Centers for Disease Control and Prevention (CDC), Children’s Mercy Hospital, University of Missouri at Kansas City […]

How the Organic Acids Test Provides Insights into Toxic Exposures 

Specific Toxic Substances and the OAT   Mold Exposure Mold exposure, often an overlooked influence on chronic illness, can be challenging to detect. The OAT can further assist in this detection process by looking at fungal activity and mycotoxin metabolism versus exclusive excretion of mycotoxins.   Specific organic acid markers such as 5-Hydroxymethyl-2-furoic acid (HMFA), Furan-2,5-dicarboxylic acid, […]

Elevated Urinary Glyphosate and Clostridia Metabolites With Altered Dopamine Metabolism in Triplets With Autistic Spectrum Disorder or Suspected Seizure Disorder: A Case Study

William Shaw, PhDIMCJ Integrative Medicine • Vol. 16, No. 1 • February 2017 Abstract Context: Autism is a neurodevelopmental disorder for which a number of genetic, environmental, and nutritional causes have been proposed. Glyphosate is used widely as a crop desiccant and as an herbicide in fields of genetically modified foods that are glyphosate resistant. Several […]

Usefulness Of HPHPA Marker In A Wide Range Of Neurological, Gastrointestinal, And Psychiatric Disorders

The dysbiosis marker 3-(3-hydroxyphenyl)-3-hydroxypropionic acid (HPHPA), the predominant dihydroxyphenylpropionic acid isomer in urine, is also measured in the Organic Acids Test offered by MosaicDX. This marker was proven by Dr. William Shaw to be due to a combination of human metabolism and the metabolism by a group of Clostridia species, including but not limited to C. […]