
Patient Opportunity
At four years old, the patient presented with severe symptoms consistent
with autism spectrum disorder that significantly affected his daily
functioning and quality of life. He experienced frequent excessive
stimming, persistent digestive discomfort, and repetitive genital
rubbing. He had no functional speech or language comprehension,
aggressive episodes that included biting, and profound emotional
dysregulation. Extended periods of inconsolable crying and self injurious
behaviors, including scratching himself, highlighted the need for a
comprehensive evaluation to identify potential underlying contributors.
Key Findings
- Organic Acids Testing (OAT) revealed markedly elevated
oxalate levels (800), indicating a significant oxalate burden. - The test also identified evidence of Clostridia bacterial
overgrowth and yeast ovegrowth. This suggests substantial
gastrointestinal microbial imbalance that may have been
contributing to the patient’s symptoms.
Approach
Treatment focused on a gradual, individualized approach due to the child’s extreme sensitivity. A low oxalate diet was introduced slowly alongside targeted gut health support to improve gastrointestinal function. Antimicrobial therapies were carefully implemented over time. Close monitoring and adjustments ensured the patient tolerated each intervention while addressing underlying microbial imbalances.
Clinical Strategy
- Gradually introduced a low oxalate diet to safely reduce the patient’s elevated oxalate burden.
- Implemented targeted gut health support to promote gastroin testinal healing and restore microbial balance.
- Initiated antimicrobial therapy slowly and strategically due to the child’s extreme sensitivity, with careful monitoring and adjustments throughout treatment.
Results
The patient’s iron levels, which had been critically low to the point that a transfusion was being considered, normalized following interventions to support gut health and reduce oxalate burden. Clinically, he demostrated significant improvements across multiple domains, including increased verbal communication, better language comprehension, greater social engagement and emotional connection. He also had a complete resolution of biting behaviors, improved emotional regulation, increased participation in daily activities, and consistent, restful sleep.
*The patient name has been changed to protect their privacy.
This material is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Use of this information is at the reader’s discretion and risk.
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