Lyme + Co-infections Comprehensive 3 day

The exact timing for a Nanotrap test after tick bite in humans has not been directly assessed. However, the Nanotrap test can definitely be run upon the earliest onset of symptoms (with or without an EM rash), as Magni et al obtained positive Nanotrap results in 100% (24/24) patients with an EM rash AND in 6/6 (100%) early onset patients presenting with joint pain or neurologic symptoms, but without an EM rash. Also, in mouse studies, viable B. burgdorferi have been detected in the bladder/urine within 7-10 days of infection.  

Mild (1+) to moderate proteinuria (2+) is not a problem, but large amounts of protein (3+) interfere with the Nanotrap assay. 

Generally: Recommend that females do not submit samples while heavy menstruation, as large amounts of blood inhibit the test. 

No, but collecting on younger children can be a bit difficult. Collecting multiple samples within a 24-hour period is okay. IFA will be hard on kids under 2, due to how antibodies are developed in children.  

No, urine specimens for Lyme + Co-infections tests should not be frozen. 

40 mL of urine is the required minimum volume for the test. 

See table below:

The Tickborne BBB Direct Detect dPCR may be performed on a single blood sample or on a series of three blood samples drawn every other day within a 5- to 8-day period. The 3-Day Draw is similar to the 1-Day Draw, except for the number of samples and the days they are drawn (i.e., Day 1, Day 3, Day 5).

Note: A 3-Day Draw cannot be performed if all three samples are collected on the same day. Samples must be drawn on different days.

Bartonella species invade the endothelial cells lining the vascular system, cycling in and out of the blood over 5 to 8 days. They evade the immune response in the bloodstream by hiding in erythrocytes and other cell types. Research suggests that a serial testing approach, which we call a 3-Day—or Triple Draw—may increase the odds of a positive dPCR result.

No, the Lyme + Co-infections tests are drop-ship only and will ship in a separate collection kit box because they have different collection needs. 

Don’t panic. Most of the materials inside the kit are still usable. The expiration date on the kit or at least one of the included tubes has expired. Please check the individual tubes before using them. If a tube is past it’s date, then they can be swapped out for standard SST tubes (yellow top, tiger top) and EDTA tubes (lavender top) as long as those tubes have not expired. Any expired tubes will be rejected per CLIA regulations. 

Yes, a licensed medical practitioner (Licensed Physicians (MD, DO), NPs, PAs, and NDs with active NPI numbers) from an eligible state is required to order testing from Mosaic. 

USA practitioners with a USA address on their account, logged into the MosaicDX practitioner portal, ordering drop ship to USA addressed patient. 

Getting tested with both direct and indirect detection methods provide a more comprehensive and accurate diagnosis, especially with infections and diseases that are difficult to detect. 

Direct Detection: 

Identifies the presence of the pathogen itself, such as with DNA, RNA, or proteins. Direct Detection can confirm that the pathogen (virus, bacteria, etc.) is currently present in your body. Best for acute infections, or cases where the pathogen is present in high enough quantities to be detected. 

Indirect Detection: 

Instead of identifying the presence of a pathogen, it looks for immune system responses that would happen when in the presence of the pathogen. Most commonly, indirect tests are used to measure the amount of antibodies in a sample. Antibodies are the proteins that the immune system typically produces to fight against antigens like bacteria or viruses. These tests can determine whether or not you have been exposed to a pathogen in the past, or even if your body is still fighting off an infection where it would be hard to detect the pathogen directly. Best for chronic or past infections in which pathogens are no longer detectable, but the immune response is. 

Visit the payment information page for an overview of payment options and procedures along with insurance coverage overview.

NOTE: Insurance coverage for testing is based on several factors such as the type of procedure, diagnosis, and insurance policy guidelines. Patients are encouraged to contact their insurance company to check for coverage and to provide the procedure codes (CPT codes) and diagnostic codes (ICD-10 codes). The CPT codes can be found on the billing information page, while ICD-10 codes are provided by the practitioner.

1. Visit AnyLabTest Now to find a location near you.
   1. Schedule an appointment online, call for assistance, or just show up for your lab test — no appointment necessary.
   2. Bring the following to your appointment:
      1. Payment for specimen collection and processing fee.
      2. Test collection kit
      3. Included gel pack (freeze ahead of time)
      4. Collection instructions
      5. Test Requisition Form with doctor’s signature
      6. UPS return bag (included in the test kit)
2. Alpha Phlebotomy Group offers three options
   1. In Home Collections – where the phlebotomist comes to you. Fees include per collection rates and mileage.
   2. Collection Draw Site Locations – where APG provides you with a location that is familiar with MosaicDX orders. Prices for collections vary by phlebotomist.
   3. Mobile Event Collections for Groups – Have a group of 20 blood collections? Create a blood draw corporate or wellness event. Events require a minimum of 6 draws per hour otherwise additional hourly fees may apply along with specific pricing per participant.
3. Los Angeles and Orange County Areas: Contact Mobile Phlebotomy Service
   1. They will complete the blood draw directly from your home. Call 909-985-5562 to make an appointment. Standard hours of operation are 6:00 a.m. to 3:00 p.m.
4. Kansas City Metro Areas: Contact Test Smartly Labs.
   1. Collection hours are Monday through Friday 9:00 a.m. to 5:00 p.m. at all four of the TSL Kansas City area locations. Call 816-800-9699 to set up your appointment.

Mosaic Diagnostics offers written interpretations within test reports and complimentary consultations with our clinical educators for qualified practitioners. To schedule a consultation, simply sign in to your MosaicDX account and book a consultation online. 

We encourage all patients to discuss results with your practitioner.

Our Resources tab also contains educational materials that you may find useful, we also offer MosaicEDGE workshops for qualified practitioners to better understand the fundamentals of lab testing.

Different states have regulations that define the scope of practice for practitioners. It is the practitioner’s responsibility to abide by these rules. Check with your state board of health to determine any restrictions related to laboratory testing. Please note, Mosaic Diagnostics does not offer testing in New York. 

Once you have opened your account, you have the options of ordering kits to stock in your office or drop-ship kits directly to your patients through your MosaicDX portal.   

Watch our short tutorial videos on how to conveniently  

• Order kit for your inventory  
• Drop-ship a kit to your patient  
• Re-order a follow-up test for your patient.    

Already have a kit? Watch this video on how to place an order for your patient using a kit from your inventory.