Mycotoxin Induced Mitochondrial Dysfunction And Cytotoxicity


Kurt Woeller, DO, FMAPS


Various mycotoxins can have significant adverse effects with regard to cellular function. Through DNA and RNA disruption and/or induction of oxidative stress mycotoxins can lead to various diseases, including cancer. A major target of intracellular mycotoxins are the mitochondria. This lecture by Dr. Kurt Woeller discussed some of the cytotoxic effects of mycotoxins on mitochondrial function.

The following Q+A is a grouping of responses from Dr. Woeller’s presentation.

Q: Is it recommended for all patients who have mycotoxins to have some form of multivitamin therapy since vitamins have a huge impact on the ECT cycle?

A: I think so. I have most everyone on foundational supplements such as a multivitamin.

Q: If you have mold and candida, do you deal with them both simultaneously, or which do you treat first generally?

A: Depends on the severity of the condition, but in general mold because it can make candida worse.

Q: Maple Syrup Urine Disease is a genetic disorder in which a person is unable to break down the branched-chain amino acids. Would riboflavin make a difference in this disorder?

A: Great question and I do not know. It probably might help some.

Q: Is any other way to measure ochratoxin than the Organic Acids Test?

A: Ochratoxin is measured on the MycoTOX Profile from GPL. The OAT does not measure Ochratoxin or any other mycotoxins.

Q: Please indicate treatment strategies for aspergillus mold exposure and mycotoxins for patients with respiratory rx MAST CIRS.

A: This is a very in-depth topic and there are some webinars on the site that address this, as well as seminars that are put on via the MosaicEDGE Workshops.

Q: I had a patient who was higher in gliotoxin than that, and we were able to completely eliminate it in less than 9 days using Ascorbic Acid and Ascorbates. We repeated this several times and got the same results using testing immediately before and immediately after the use of IV-Vitamin C. The whole process took about 9 or 10 days.

A: Awesome. I do see the value in ascorbic acid intervention too.

The material contained within this article and webinar is not intended to replace the services and/or medical advice of a licensed healthcare practitioner, nor is it meant to encourage diagnosis and treatment of disease. It is for educational purposes only. Any application of suggestions set forth in the following portions of this article is at the reader’s discretion and sole risk. Implementation or experimentation with any supplements, herbs, dietary changes, medications, and/or lifestyle changes, etc., is done so at your sole risk and responsibility.

Kurt Woeller DO

About the Author

Kurt Woeller, DO, FMAPS

Kurt N. Woeller, DO, FMAPS, is a Doctor of Osteopathic Medicine, integrative and functional medicine physician, and biomedical Autism Treatment Specialist in clinical practice for over 25 years.

Dr. Woeller is the education director and main course developer for his Integrative Medicine Academy (https://integrativemedicineacademy.com), an online academy for health professionals. He is also the Organic Acids Test (OAT) seminar creator and presenter for Mosaic Diagnostics Laboratory (formally Great Plains Laboratory’s GPL Academy) Mosaic EDGE seminars and has been involved in monthly educational webinars for GPL/Mosaic Diagnostics, and other organizations for over a decade.

His private practice, Sunrise Functional Medicine (https://mysunrisecenter.com), focuses on specialized diagnostic testing and treatments for individuals with complex medical conditions like autism, autoimmune, gastrointestinal, certain neurological disorders, and other chronic health conditions. Dr. Woeller is a Fellow of the Medical Academy of Pediatric Special Needs (MAPS).

He has served as a clinical consultant for various laboratory companies, i.e., Great Plains Laboratory, BioHealth Laboratory, providing health practitioner education regarding functional and integrative medicine.

You can follow Dr. Woeller for ongoing education articles and videos through his Substack at https://drwoeller.substack.com/ and his YouTube channel for Integrative Medicine Academyhttps://www.youtube.com/@integrativemedicineacademy. Finally, listen to Dr. Woeller’s latest health professional interviews through his Functional Medicine Doc Talk Podcast – https://functionalmedicinedoctalk.com.