Multivesicular bodies (MVBs) are components of the endocytic pathway which are critical for cellular signaling pathways, bundling of molecules for specialized purposes, receptor recycling, etc. With fusion of MVBs to the plasma membrane the release of exosomes occurs which influence the cell-to-cell communication system. Exosomes can be transported through the body and play a role in normal physiology, as well as disease. For example, exosomes can facilitate cell-to-cell transport of disease-related proteins such as prions and beta-amyloid proteins. This webinar will explore some of the fascinating details of exosomes and their link to various diseases.

Q: Is there any way to put targeted molecules into exosomes to target diseases?

A: This is ongoing research and appears to be the goal for many things such as cancer therapy.


Q: Have you heard of plasmalogens and Dr. Dayan Goodenowe’s work? If so, what do you think about his test and supplements?

A: I have heard of plasmalogens, but not this doctor. Will do some research into this.


Q: Does that mean plant-based diets are not good?

A: A plant-based diet or mostly a plant-based diet is essential for health. It is plant-based foods that appear to have a health-promoting effect on the digestive system microbiome. It appears that with a healthy and diverse microbiome we are likely producing exosomes that are also health promoting.


Q: Do individuals who have recovered from COVID-19 also produce exosomes?

A: Every cell can produce exosomes throughout our lifetime. The mechanisms involved in exosome production are intimately linked to the moment-to-moment existence of cells.