The material contained within this presentation is not intended to replace the services and/or medical advice of a licensed healthcare practitioner, nor is it meant to encourage diagnosis and treatment of disease. It is for educational purposes only. Any application of suggestions set forth in the following portions of this article is at the reader’s discretion and sole risk. Implementation or experimentation with any supplements, herbs, dietary changes, medications, and/or lifestyle changes, etc., is done so at your sole risk and responsibility. Views expressed are those of the presenter and not necessarily those of Mosaic Diagnostics.
This is an automated AI transcript of the Webinar video seen above. For the most accurate account of Dr. Koz’s presentation on, please watch the webinar video on this page.
Webinar Transcript
Good afternoon everybody. Thank you so much for joining us for our webinar today. We will give everybody just another minute to filter in, and then we will kick it off seeing people trickling in.
Excellent. So let me go ahead and introduce our speaker and do some housekeeping, and then we’ll let Dr. Koz take it away.
We will be having a Q and A at the end of this with as much time left as we have. So anytime during the presentation, if you want to submit a question, you can put it either into the chat or into the Q and A. I’ll be monitoring both of those. And so, we’ll get to as many of those as we possibly can.
So let me go ahead and introduce our speaker. Dr. Peter Kozlowski is a distinguished functional medicine practitioner with over a decade of expertise dedicated to transforming healthcare. As a seasoned professional, Dr. Koz has become a trusted figure in the field, blending traditional medical knowledge with innovative, innovative approaches to address the root causes of health issues.
Under the mentorship of renowned figures such as Dr. Mark Hyman, Dr. Deepak Chopra, and Dr. Susan Blum, he honed his skills and developed a unique perspective on comprehensive patient care. Dr. Kozlowski has authored two wonderful and impactful books: Unfunny Your Gut and Get the Func Out. They’re both available on Amazon—highly, highly recommend them. His work delves into the interconnectedness of these systems and how to identify imbalances that lead to chronic disease.
We are incredibly happy to welcome Dr. Koz to our virtual stage today. Dr. Koz, the floor is yours.
Awesome. Thank you, Michelle. Thank you Mosaic for having me. Thank you everyone for attending. I love functional medicine. I love functional medicine testing. I love talking about it. I hope that you guys learn stuff as I’m talking. Please, submit questions. Whatever it is, I’d love to answer it at the end. And so let’s dive in.
We’re gonna talk today about turning chaos to clarity, simplifying complex patients and labs, to resolve chronic symptoms with functional medicine. And if you’re practicing functional medicine or traditional medicine, you know that our patients are not simple. And if you’re just getting started or you’re in the early stages, the labs can be really confusing. The labs can sometimes feel more complex even than the patient, and they don’t have to be that way. My passion has always been trying to take complex subjects and make ’em easier to understand. So that’s what we’re gonna try to do today.
We’re gonna use a case study, very common type of patient that we see. And I look forward to you guys hopefully learning a lot.
So we’re gonna talk about the OAT test, the mycotoxin test, the TOXDetect, how I use them, in the presence of which chronic symptoms. When we do find stuff like candida overgrowth or mitochondrial dysfunction or toxic burden, I will talk about strategies that I use to treat those different things. Most of them you can treat at the same time. There are different ways to treat these things. My ways are not the only ways. You know, the best piece of advice I could probably give is learn different ways. Offer them to patients, and then meet the patient where they are at, right? Some people will be very strict, like, I only want to do diet, or I only want to use supplements, or, I’m okay with meds, or, I wanna do this first or that first. It’s, it’s, I never try to fight with my patients. I try to figure out where they’re at. I think our greatest job is education—to educate our patients about their options. I hate telling people what to do. Not everybody loves that. A lot of patients just wanna be told what to do. But for me it’s always, you know, I don’t want to push something on someone if they’re not ready to do it, ’cause it’s not gonna work. But we’ll talk about strategies and we’ll talk about these tests.
So, today we’re gonna talk about Mary, a 37‑year‑old female who came in to discuss fatigue, muscle weakness, joint pain, feeling cold tingling. She has headaches, acne, brain fog, tremor, and she’s constipated. And she wants to address all of that at today’s visit and get better right away.
So the first thing I always start with is every visit I start is, “What are your goals and expectations?”, right? We’ve been blessed with a lot of really good reviews. So people come in with pretty high expectations, but I always like to set it up, right? Like, this is a process, right? Your outcome is really gonna be dependent on the work you put in. I don’t have magic pills. I have the right tests to guide you, right? And then it’s really up to you to get better, right? If you’re looking for a magic pill, I’m not the person. And so I love starting with just, you know, laying out expectations—’cause, you know, reality is that we’re probably not gonna get all these symptoms to go away a week later. So it takes time.
History: Her symptoms started three months ago. In that time she has been to:
- A neurologist
- An endocrinologist
- An OB‑GYN
- A gastroenterologist
- A rheumatologist
- An infectious disease doctor
- A chiropractor
- The ER three times
- Her primary care provider six times
So there’s a lot going on. Every one of those doctors told her nothing was wrong, and that she should take an anxiety medication. So she comes in pretty upset—most of my patients come in, they don’t like their doctors. There’s a lot of lack of trust. She’s been online a lot, which is also very common for my patients: they think they’re doctors, they know how to treat themselves based on everything they’re reading on the internet. She’s on ten supplements that she’s self‑prescribed, but she’s still here and doesn’t know what to do. The supplements aren’t helping. She didn’t start the anxiety medicine. She doesn’t believe the crew of doctors who told her nothing’s wrong.
So a lot of people come in assuming I’ll give them a suitcase full of supplements—that’s not what I do. I want to understand the why. That’s where Mosaic comes in—it’s all about testing. Honestly, the first visit with me is typically just education about all these different things, and figuring out the right testing to order.
Key personal history:
- EKG, MRI of her brain, CT—all normal
- History of uterine septum surgery 5 years ago
- Parents had cancer at older age; her kids have eczema
- Sleeps 6–7 hours/night; exercises 3–4×/week
- Does not smoke, chew tobacco, use drugs, or drink
- History of a root canal and crown caps on her teeth
- Married with two children; Christian
- Went dairy‑ and gluten‑free before coming in
- Grew up with a lot of anxiety
- OB history: 3 babies in 3½ years (stillbirth 3 years ago; healthy boy via C‑section 2 years ago; healthy girl 1 year ago)
- First menstrual cycle in over 3 years returned 3 months ago—correlates exactly with symptom onset
- High stress: two kids under two; unresolved grief from stillbirth and childhood anxiety
- Moved into a newly renovated home 1 year ago—found water damage and mold in basement
Root‑cause framework:
- Food sensitivities
- Gut health
- Hormone imbalances
- Environmental toxins
- Mental, emotional, spiritual, and social health
(Plus, in the last year and a half: genetics as a 6th)
Food sensitivities
I test everyone—delayed reactions (hours to days) can trigger migraines, eczema, etc., with no obvious link. I use Mosaic’s dried blood‑spot test: 5 drops of finger‑prick blood, sent back for results in a week. Mary declined—she was convinced only gluten and dairy mattered. I disagreed, but didn’t argue. Always start here—if daily foods are making someone sick, nothing else will help.
Gut health / Candida
Symptoms of candida are broad: fatigue, bloating, constipation/diarrhea, brain fog, skin issues, mood swings, sugar cravings, urinary symptoms, allergies, etc.
Best test: OAT (organic acids). Candida thrives on sugar and when immunity is suppressed (cortisol). Mary’s OAT came back 67 (mild; 50–100 mild, 100–150 moderate, >150 severe). We have something to treat.
Hormones
Mary’s labs:
- TPO antibodies 1,032 (high)
- TSH normal; free T₄ normal; free T₃ normal → suboptimal T₄→T₃ conversion
- Progesterone 0.5 (day‑21 test; should be ~15) → significant estrogen dominance
- Estradiol 185; LH 6.6; FSH 2.2
She’s not on thyroid meds yet—this is euthyroid with antibodies (pre‑Hashimoto). We’ll treat root causes first (toxins, candida, stress) and monitor. For estrogen dominance, we’ll use bioidentical progesterone (50 mg days 14–28 of cycle) and retest.
Environmental toxins
- Mold/Mycotoxins: MycoTOX panel → elevated aflatoxin, ochratoxin, mycophenolic acid → likely active exposure; must test home remediation
- ToxDetect: Elevated perchlorate (fires, dairy feed), moderate phthalates (packaging, plastics, beauty products), BPS (receipts, containers)
- Glyphosate: Detected in 81% of U.S. urine samples (CDC 2022). Mosaic offers a home‑water test.
Mental/emotional/spiritual/social
First step: admit there’s a problem. On IFM intake, if someone says “No stress” + “I manage stress easily,” that’s denial. Key to treating candida, toxins, hormones is activating the parasympathetic nervous system (HRV biofeedback, breathing exercises, etc.).
Summary of orders for Mary
- Food sensitivity: declined
- Gut health: OAT (positive for candida)
- Hormones: day‑21 panel (suboptimal thyroid conversion; very low progesterone)
- Toxins: MycoTOX panel; TOXDetect; glyphosate levels
- Mental/emotional: counseling, stress‑management education
Treatment plan
- Candida (OAT positive):
- Nystatin 1 tablet TID × 90 days, 2‑week break, repeat OAT
- Soil‑/spore‑based probiotic nightly
- Binder (zeolite clay or activated charcoal)
- Simplified anti‑candida food plan (avoid sugar overload, but don’t stress diet)
- Mitochondrial support: CoQ₁₀ 100–300 mg/day (or equivalent nutraceutical blend)
- Methylation support: Methyl B12 + folate (or full genetic/methylation panel if indicated)
- Mycotoxins:
- Test home remediation first
- Infrared sauna 20 min/day
- Binder + glutathione support
- Phase I/II/III detox support + lifestyle (hydration, bowel regularity, sweat)
- Thyroid: Treat toxins + candida → retest antibodies & T₄→T₃ conversion
- Estrogen dominance: Bioidentical progesterone 50 mg days 14–28 of cycle → retest
Through advanced testing we found subclinical thyroid dysfunction with antibodies, estrogen dominance, candida overgrowth, mitochondrial dysfunction, a likely methylation defect, and multiple environmental toxins. All of these explain her “normal” but debilitating symptoms—and give us targeted interventions that are already improving her health.
Thank you, and now let’s open up for questions.
